First, they came for C compilers and you said nothing. Then, they came for Python interpreters and you said nothing. Now that they are coming for Excel, who will defend you?
You're making a joke, but when you look at what's happening with software licenses (mostly in AI) that restrict uses to those that the releasing companies deem appropriate (such as nonsensically no use in the nuclear industry) it's only a matter of time until political completely creeps into the software supply chain and all your python packages will have their own specific political list of what you can and can't do with them.
Minimizing dependencies is going to become increasingly important.