You could be seeing two different sets of people, largely non overlapping.

Ozempic and other research peptides are very popular in online biohacking communities. The same communities were against vaccines. This paradox has been pointed out quite often and it became a meme.

Are they against vaccines in general or just the mRNA ones? Because for the covid vaccines, what I saw was almost entirely anti-mRNA.

The typical argument was that all the various types of covid vaccines had been fast tracked and safety data was insufficient; hence the irony.

If people were compelled to take Ozempic to keep their jobs, there would be "issues".

What makes you think these two are comparable? Just that they are drugs? No one is requiring anyone to take these drugs -- people are coming to the conclusion on their own. And a lot of people taking these drugs are not paying the companies that own the production of them. The rapid rise in compounding pharmacies (think of these as "wildcat" pharmacies) producing these drugs is currently causing an opportunity cost to the owners of patents of these drugs. There really isn't any conspiracy here.

And there is no shortage of moralizing and FUD about these drugs. Just read this comment thread.